Science With Purpose

We believe the best science happens in environments built on curiosity, collaboration, and trust.
We believe the best science happens in environments built on curiosity, collaboration, and trust.

OUR MISSION

Our mission is to unlock the next wave of immunotherapy. We believe that meaningful and durable cures can be achieved by taking advantage of the millions of years of evolution between microbes and the human immune system to target unconventional T cells against cancer.
Our mission is to unlock the next wave of immunotherapy. We believe that meaningful and durable cures can be achieved by taking advantage of the millions of years of evolution between microbes and the human immune system to target unconventional T cells against cancer.

Laguna is a biotechnology company developing next-generation attenuated microbial platforms that have the predictable PK/PD of small molecule drugs and activate the precise combination of signals required for T cells to find and kill cancer. By combining insights from microbiology, immunology, and cancer biology we are building a new class of immunotherapies designed to be safer, accessible, scalable, and effective across multiple cancer types.

In our pursuit of this mission, we are guided by these values:

Laguna is a biotechnology company developing next-generation attenuated microbial platforms that have the predictable PK/PD of small molecule drugs and activate the precise combination of signals required for T cells to find and kill cancer. By combining insights from microbiology, immunology, and cancer biology we are building a new class of immunotherapies designed to be safer, accessible, scalable, and effective across multiple cancer types.

In our pursuit of this mission, we are guided by these values:

ask why

Progress starts with questions. In the clinic, the lab, and the boardroom, curiosity helps us understand disease more clearly and discover new paths forward. We are committed to open, good-faith conversations where curiosity is met with transparency. Together, we seek to understand not just what we do, but the deeper reasons behind it.

Be a Wayfinder

We respect the therapeutic journeys blazed before us, and imagine new and creative directions forward. We build on what has been learned before, but  when existing therapies are insufficient, we embrace the unknown, charting a course off the beaten path to discover and engineer better ways forward.

Raise the Standard

show up for each other

We hold ourselves and each other to the absolute highest standards of scientific accuracy and ethical integrity. Patients depend on the rigor of our work. From early discovery through clinical care, we thoroughly approach every challenge with transparency to ensure that patients can rely on our solutions.

Breakthroughs are rarely the work of one person. We actively support one another, share our ideas openly, and assume the best intentions. We are dedicated to cultivating an environment where the success of the team is achieved when everyone feels valued, inspired, and equipped to do their very best work.

Show up for each other

show up for each other

raise the standard

Breakthroughs are rarely the work of one person. We actively support one another, share our ideas openly, and assume the best intentions. We are dedicated to cultivating an environment where the success of the team is achieved when everyone feels valued, inspired, and equipped to do their very best work.

We hold ourselves and each other to the absolute highest standards of scientific accuracy and ethical integrity. Patients depend on the rigor of our work. From early discovery through clinical care, we thoroughly approach every challenge with transparency to ensure that patients can rely on our solutions.

Team

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Jonathan Kotula, PhD

CEO and Co-Founder

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Russell Carrington, PhD

COO and Co-Founder

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Dan Portnoy, PhD

Scientific Advisor and Co-Founder

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Barbara Troupin, MD/MBA

Senior Clinical Advisor

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Chris Rae, PhD

Director of Microbiology

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Jim Adair

Fractional CBO

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Ly Kawaguchi

ClinOps Advisor

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Ed Lemmens, MS

Immunology

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Jonathan Kotula, PhD

CEO and Co-Founder

user pic

Russell Carrington, PhD

COO and Co-Founder

user pic

Dan Portnoy, PhD

Scientific Advisor and Co-Founder

user pic

Barbara Troupin, MD/MBA

Senior Clinical Advisor

user pic

Chris Rae, PhD

Director of Microbiology

user pic

Jim Adair

Fractional CBO

user pic

Ly Kawaguchi

ClinOps Advisor

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Ed Lemmens, MS

Immunology

Our Partners

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